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Vecuronium
Norcuron (vecuronium) is a small molecule pharmaceutical. Vecuronium was first approved as Norcuron on 1984-04-30.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Vecuronium bromide
Tradename
Company
Number
Date
Products
NORCURONOrganonN-018776 DISCN1984-04-30
2 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
vecuronium bromideANDA2023-01-18
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
M03: Muscle relaxants
M03A: Muscle relaxants, peripherally acting agents
M03AC: Other quaternary ammonium compounds in atc, muscle relaxants, peripherally acting
M03AC03: Vecuronium
HCPCS
No data
Clinical
Clinical Trials
84 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Septic shockD012772A48.3332511
Heart arrestD006323EFO_0009492I46224119
ShockD012769R57.11213
Acute kidney injuryD058186HP_0001919N17112
EndotoxemiaD01944611
HemorrhageD006470MP_0001914R5811
Surgical blood lossD01606311
General anesthesiaD00076811
Artificial respirationD01212111
Pulmonary arterial hypertensionD00008102911
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Autism spectrum disorderD000067877F84.01213
Congenital heart defectsD006330HP_0001627Q24.9111
Heart diseasesD006331EFO_0003777I51.911
Autistic disorderD001321EFO_0003758F84.0111
Pleural effusionD010996J90111
SepsisD018805A41.9111
HypovolemiaD020896HP_0011106E86111
Hemorrhagic shockD012771111
Spontaneous abortionD000022EFO_1001255O00.111
VasoplegiaD05698711
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Traumatic shockD012774T79.4112
HypertensionD006973EFO_0000537I10112
Acute lung injuryD055371EFO_000461011
Pulmonary hypertensionD006976EFO_0001361I27.2011
Acute painD059787R52111
Out-of-hospital cardiac arrestD05868711
Major depressive disorderD003865EFO_0003761F2211
Chronic kidney failureD007676EFO_0003884N18.611
Heart failureD006333EFO_0003144I5011
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients279
HypotensionD007022EFO_0005251I95134
Social psychologyD01159322
Wounds and injuriesD014947T14.811
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MyomaD009214D2122
Rotator cuff tear arthropathyD00007065611
SchizophreniaD012559EFO_0000692F2011
Placenta previaD010923EFO_0007442O4411
HyponatremiaD007010HP_0002902E87.111
HypernatremiaD006955HP_0003228E87.011
Liver failureD017093HP_0001399K72.911
PainD010146EFO_0003843R5211
Induced abortionD00002811
Traumatic brain injuriesD000070642S0611
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVECURONIUM
INNvecuronium bromide
Description
Vecuronium bromide is the organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium substituents. It has a role as a nicotinic antagonist, a neuromuscular agent and a muscle relaxant. It is a quaternary ammonium salt and an organic bromide salt. It contains a vecuronium. It is functionally related to a 5alpha-androstane.
Classification
Small molecule
Drug classquaternary ammonium derivatives: neuromuscular blocking agents; quaternary ammonium derivatives: neuromuscular blocking agents
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@H]([N+]3(C)CCCCC3)[C@@H]4OC(C)=O)[C@@]2(C)C[C@@H]1N1CCCCC1
Identifiers
PDB
CAS-ID50700-72-6
RxCUI11153
ChEMBL IDCHEMBL1201219
ChEBI ID9939
PubChem CID39764
DrugBankDB01339
UNII ID7E4PHP5N1D (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 6,273 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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161 adverse events reported
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