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Tridihexethyl
Pathilon (tridihexethyl) is a small molecule pharmaceutical. Tridihexethyl was first approved as Pathilon on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Tridihexethyl chloride
Tradename
Company
Number
Date
Products
PATHILONLederle LaboratoriesN-009489 DISCN1982-01-01
1 products
PATHILONLederle LaboratoriesN-009729 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
A03: Drugs for functional gastrointestinal disorders
A03A: Drugs for functional gastrointestinal disorders
A03AB: Synthetic anticholinergics, quaternary ammonium compounds for functional gastrointestinal disorders
A03AB08: Tridihexethyl
HCPCS
No data
Clinical
Clinical Trials
167 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Dental plaqueD0037731103115
Acne vulgarisD000152EFO_0003894L701117110
Facial painD005157R51.9131159
GingivitisD005891K05.102619
Surgical wound infectionD0135302316
Periodontal diseasesD010510K05.63115
MelanosisD008548EFO_0003963L81.11113
Seborrheic dermatitisD012628L21112
Aggressive periodontitisD010520EFO_0006342K05.211
Ulcerative colitisD003093EFO_0000729K5111
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Temporomandibular joint disordersD013705M26.63331218
Gingival diseasesD005882K05.166
PsoriasisD011565EFO_0000676L402114
Cardiovascular diseasesD002318EFO_0000319I981112
Peri-implantitisD057873EFO_1001390112
Covid-19D000086382U07.1112
InfertilityD007246EFO_0000545111
ElectromyographyD004576111
CannabisD002188111
PeriodontitisD010518EFO_0000649K05.311
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sleep bruxismD020186G47.631135
Healthy volunteers/patients414
Coronavirus infectionsD018352EFO_0007224B34.211
Arsenic poisoningD020261T57.011
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Stomatognathic diseasesD009057K08.911
Obstructive sleep apneaD020181EFO_0003918G47.3311
Chronic diseaseD00290811
Craniomandibular disordersD01727111
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Dental cariesD003731EFO_0003819K0244
BruxismD002012F45.833
MyalgiaD063806HP_0003326M79.122
PainD010146EFO_0003843R5222
Personal satisfactionD01054922
Chronic painD059350HP_001253222
PulpitisD011671EFO_1001139K04.022
Postoperative painD010149G89.1822
Edentulous jawD00757522
Edentulous mouthD00906622
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTRIDIHEXETHYL
INN
Description
Tridihexethyl is a tertiary alcohol and a quaternary ammonium ion. It has a role as an anti-ulcer drug, a muscarinic antagonist and an antispasmodic drug.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC[N+](CC)(CC)CCC(O)(c1ccccc1)C1CCCCC1
Identifiers
PDB
CAS-ID60-49-1
RxCUI38617
ChEMBL IDCHEMBL1201354
ChEBI ID9701
PubChem CID20299
DrugBankDB00505
UNII ID
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 24 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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868 adverse events reported
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