In the BioHarmony Drug Report Database

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Trametinib

Mekinist (trametinib) is a small molecule pharmaceutical. Trametinib was first approved as Mekinist on 2013-05-29. It is used to treat melanoma and non-small-cell lung carcinoma in the USA. It has been approved in Europe to treat melanoma. The pharmaceutical is active against dual specificity mitogen-activated protein kinase kinase 1 and dual specificity mitogen-activated protein kinase kinase 2. In addition, it is known to target serine/threonine-protein kinase B-raf. Mekinist’s patents are valid until 2033-08-30 (FDA).

 

Trade Name

 

Mekinist
 

Common Name

 

trametinib
 

ChEMBL ID

 

CHEMBL2103875
 

Indication

 

melanoma, non-small-cell lung carcinoma
 

Drug Class

 

Tyrosine kinase inhibitors: mitogen-activated protein (MAP) kinase inhibitors

Image (chem structure or protein)

Trametinib structure rendering