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Thiethylperazine
Torecan (thiethylperazine) is a small molecule pharmaceutical. Thiethylperazine was first approved as Torecan on 1982-01-01. It is used to treat nausea, vertigo, and vomiting in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
otorhinolaryngologic diseasesD010038
nervous system diseasesD009422
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Thiethylperazine malate
Tradename
Company
Number
Date
Products
TORECANNovartisN-012754 DISCN1982-01-01
1 products
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Thiethylperazine maleate
Tradename
Company
Number
Date
Products
TORECANNovartisN-012753 DISCN1982-01-01
1 products
TORECANNovartisN-013247 DISCN1982-01-01
1 products
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
nauseaHP_0002018D009325R11.0
vertigo—D014717H81.39
vomitingHP_0002013D014839R11.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
R: Respiratory system drugs
— R06: Antihistamines for systemic use
— R06A: Antihistamines for systemic use
— R06AD: Phenothiazine derivatives, systemic antihistamines
— R06AD03: Thiethylperazine
HCPCS
Code
Description
J3280
Injection, thiethylperazine maleate, up to 10 mg
Q0174
Thiethylperazine maleate, 10 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at the time of chemotherapy treatment, not to exceed a 48 hour dosage regimen
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTHIETHYLPERAZINE
INNthiethylperazine
Description
Thiethylperazine is a member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2. It has a role as a phenothiazine antipsychotic drug, a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist and an antiemetic. It is a member of phenothiazines and a N-methylpiperazine. It is functionally related to a perazine.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCSc1ccc2c(c1)N(CCCN1CCN(C)CC1)c1ccccc1S2
Identifiers
PDB—
CAS-ID1420-55-9
RxCUI10471
ChEMBL IDCHEMBL1378
ChEBI ID9544
PubChem CID5440
DrugBankDB00372
UNII ID8ETK1WAF6R (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 224 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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71 adverse events reported
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