In the BioHarmony Drug Report Database

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Tacrolimus

Astagraf Xl, Envarsus, Prograf, Protopic, Advagraf, Modigraf (tacrolimus) is a small molecule pharmaceutical. Tacrolimus was first approved as Astagraf Xl on 1994-04-08. It is used to treat atopic dermatitis and graft vs host disease in the USA. It has been approved in Europe to treat atopic dermatitis, graft rejection, kidney transplantation, and liver transplantation. The pharmaceutical is active against peptidyl-prolyl cis-trans isomerase FKBP1A. Prograf’s patents are valid until 2028-08-30 (FDA).

 

Trade Name

 

Advagraf, Envarsus, Modigraf, Protopic
 

Common Name

 

tacrolimus
 

ChEMBL ID

 

CHEMBL3989887
 

Indication

 

atopic dermatitis, graft rejection, graft vs host disease, kidney transplantation, liver transplantation
 

Drug Class

 

Immunosuppressives: immunosuppressant, rapamycin derivatives

Image (chem structure or protein)

Tacrolimus structure rendering