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Suxamethonium
Suxamethonium is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against acetylcholine receptor subunit alpha.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
M03: Muscle relaxants
M03A: Muscle relaxants, peripherally acting agents
M03AB: Choline derivative muscle relaxants, peripherally acting
M03AB01: Suxamethonium
HCPCS
No data
Clinical
Clinical Trials
33 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Neuromuscular blockadeD01914811226
DepressionD003863F33.9123
Cesarean sectionD00258522
AnesthesiaD00075822
Rapid sequence induction and intubationD000079603112
PregnancyD011247EFO_0002950Z33.111
Intratracheal intubationD00744211
Postoperative complicationsD01118311
IntubationD00744011
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
General anesthesiaD00076811
MyalgiaD063806HP_0003326M79.111
StrokeD020521EFO_0000712I63.911
ShockD012769R57.111
Wounds and injuriesD014947T14.811
ComaD003128HP_0001259R40.211
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
BradycardiaD001919HP_0001662R00.111
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Patient satisfactionD01706022
PharyngitisD010612R07.011
FasciculationD005207R25.311
Adrenal insufficiencyD00030911
Pulmonary atelectasisD001261J98.111
PainD010146EFO_0003843R5211
ManiaD000087122F3011
HallucinationsD006212HP_0000738F06.011
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSUXAMETHONIUM
INNsuxamethonium chloride
Description
Succinylcholine is a quaternary ammonium ion that is the bis-choline ester of succinic acid. It has a role as a neuromuscular agent, a muscle relaxant and a drug allergen. It is a quaternary ammonium ion and a succinate ester.
Classification
Small molecule
Drug classquaternary ammonium derivatives; quaternary ammonium derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
Identifiers
PDB2HA2
CAS-ID306-40-1
RxCUI10154
ChEMBL IDCHEMBL703
ChEBI ID45652
PubChem CID5314
DrugBankDB00202
UNII IDI9L0DDD30I (ChemIDplus, GSRS)
Target
Agency Approved
CHRNA1
CHRNA1
Organism
Homo sapiens
Gene name
CHRNA1
Gene synonyms
ACHRA, CHNRA
NCBI Gene ID
Protein name
acetylcholine receptor subunit alpha
Protein synonyms
acetylcholine receptor, nicotinic, alpha 1 (muscle), cholinergic receptor, nicotinic alpha 1, cholinergic receptor, nicotinic, alpha 1 (muscle), cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), muscle nicotinic acetylcholine receptor, nicotinic acetylcholine receptor alpha subunit, nicotinic cholinergic receptor alpha 1
Uniprot ID
Mouse ortholog
Chrna1 (11435)
acetylcholine receptor subunit alpha (P04756)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,496 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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29,825 adverse events reported
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