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Sodium phenylbutyrate

Buphenyl, Ammonaps, Pheburane (sodium phenylbutyrate) is a small molecule pharmaceutical. Sodium phenylbutyrate was first approved as Buphenyl on 1996-04-30. It is used to treat beta-thalassemia, cystic fibrosis, myeloproliferative disorders, and sickle cell anemia in the USA. It has been approved in Europe to treat carbamoyl-phosphate synthase i deficiency disease, citrullinemia, and ornithine carbamoyltransferase deficiency disease.

 

Trade Name

 

Ammonaps, Pheburane
 

Common Name

 

sodium phenylbutyrate
 

ChEMBL ID

 

CHEMBL1746
 

Indication

 

beta-thalassemia, carbamoyl-phosphate synthase i deficiency disease, citrullinemia, cystic fibrosis, myeloproliferative disorders, ornithine carbamoyltransferase deficiency disease, sickle cell anemia
 

Drug Class

 

Image (chem structure or protein)

Sodium phenylbutyrate structure rendering