In the BioHarmony Drug Report Database

"Preview" Icon

Sildenafil

Revatio, Viagra (sildenafil) is a small molecule pharmaceutical. Sildenafil was first approved as Revatio on 1998-03-27. It is used to treat pulmonary hypertension and vasculogenic impotence in the USA. It has been approved in Europe to treat erectile dysfunction and pulmonary hypertension. The pharmaceutical is active against cGMP-specific 3′,5′-cyclic phosphodiesterase. In addition, it is known to target solute carrier organic anion transporter family member 1B3, cone cGMP-specific 3′,5′-cyclic phosphodiesterase subunit alpha’, solute carrier organic anion transporter family member 2B1, and multidrug resistance-associated protein 5.

 

Trade Name

 

Revatio, Viagra
 

Common Name

 

sildenafil
 

ChEMBL ID

 

CHEMBL192
 

Indication

 

erectile dysfunction, pulmonary hypertension, vasculogenic impotence
 

Drug Class

 

Pde5 inhibitors

Image (chem structure or protein)

Sildenafil structure rendering