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Rocuronium
Zemuron (rocuronium) is a small molecule pharmaceutical. Rocuronium was first approved as Zemuron on 1994-03-17.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Rocuronium bromide
Tradename
Company
Number
Date
Products
ZEMURONOrganonN-020214 DISCN1994-03-17
3 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
rocuronium bromideANDA2023-05-09
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M03: Muscle relaxants
— M03A: Muscle relaxants, peripherally acting agents
— M03AC: Other quaternary ammonium compounds in atc, muscle relaxants, peripherally acting
— M03AC09: Rocuronium bromide
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Premature obstetric laborD007752O60———112
Premature birthD047928EFO_0003917O60———1—1
Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PregnancyD011247EFO_0002950Z33.1————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameROCURONIUM
INNrocuronium bromide
Description
Rocuronium bromide is the organic bromide salt of a 5alpha androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents. It has a role as a neuromuscular agent and a muscle relaxant. It is an organic bromide salt and a quaternary ammonium salt. It contains a rocuronium. It derives from a hydride of a 5alpha-androstane.
Classification
Small molecule
Drug classquaternary ammonium derivatives: neuromuscular blocking agents; quaternary ammonium derivatives: neuromuscular blocking agents
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C=CC[N+]1([C@H]2C[C@H]3[C@@H]4CC[C@H]5C[C@H](O)[C@@H](N6CCOCC6)C[C@]5(C)[C@H]4CC[C@]3(C)[C@H]2OC(C)=O)CCCC1
Identifiers
PDB—
CAS-ID119302-91-9
RxCUI32521
ChEMBL IDCHEMBL1201244
ChEBI ID8884
PubChem CID441351
DrugBankDB00728
UNII IDI65MW4OFHZ (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 10,341 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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225 adverse events reported
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