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Quinethazone
Hydromox (quinethazone) is a small molecule pharmaceutical. Quinethazone was first approved as Hydromox on 1982-01-01. It is used to treat edema, heart failure, hypertension, and nephrotic syndrome in the USA.
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Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Quinethazone
Tradename
Company
Number
Date
Products
HYDROMOXLederle LaboratoriesN-013264 DISCN1982-01-01
1 products
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Quinethazone
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Reserpine
Tradename
Company
Number
Date
Products
HYDROMOX RLederle LaboratoriesN-013927 DISCN1982-01-01
1 products
Hide discontinued
Labels
FDA
EMA
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
edemaD004487R60.9
heart failureEFO_0003144D006333I50
hypertensionEFO_0000537D006973I10
nephrotic syndromeEFO_0004255D009404N04
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
C03: Diuretics
C03B: Low-ceiling diuretics, excl. thiazides
C03BA: Sulfonamides, low-ceiling diuretics, plain
C03BA02: Quinethazone
C03BB: Sulfonamides and potassium in combination, low-ceiling diruetics, excluding thiazides
C03BB02: Quinethazone and potassium
HCPCS
No data
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameQUINETHAZONE
INNquinethazone
Description
Quinethazone is a member of the class of quinazolines that is quinazolin-4-one substituted at positions 2, 6 and 7 by ethyl, sulfamoyl and chloro groups respectively; a thiazide-like diuretic used to treat hypertension. It has a role as an antihypertensive agent and a diuretic.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCC1NC(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N1
Identifiers
PDB
CAS-ID73-49-4
RxCUI59743
ChEMBL IDCHEMBL1532
ChEBI ID8717
PubChem CID6307
DrugBankDB01325
UNII ID455E0S048W (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 58 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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10 adverse events reported
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