In the BioHarmony Drug Report Database

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Pexidartinib

Turalio (pexidartinib) is a small molecule pharmaceutical. Pexidartinib was first approved as Turalio on 2019-08-02. It is used to treat giant cell tumor of tendon sheath in the USA. The pharmaceutical is active against mast/stem cell growth factor receptor Kit and macrophage colony-stimulating factor 1 receptor. In addition, it is known to target tyrosine-protein kinase Lck, NT-3 growth factor receptor, vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 1, receptor-type tyrosine-protein kinase FLT3, and cyclin-dependent kinase 19. Turalio’s patents are valid until 2038-07-24 (FDA).

 

Trade Name

 

Turalio
 

Common Name

 

pexidartinib
 

ChEMBL ID

 

CHEMBL3813873
 

Indication

 

giant cell tumor of tendon sheath
 

Drug Class

 

Tyrosine kinase inhibitors

Image (chem structure or protein)

Pexidartinib structure rendering