In the BioHarmony Drug Report Database

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Pemetrexed

Pemetrexed, Pemfexy, Alimta, Armisarte, Pemetrexed Actavis (pemetrexed) is a small molecule pharmaceutical. Pemetrexed was first approved as Pemetrexed on 2004-09-20. It is used to treat mesothelial neoplasms and non-small-cell lung carcinoma in the USA. It has been approved in Europe to treat mesothelioma and non-small-cell lung carcinoma. The pharmaceutical is active against dihydrofolate reductase. In addition, it is known to target thymidylate synthase, proton-coupled folate transporter, and trifunctional purine biosynthetic protein adenosine-3. Alimta’s patents are valid until 2035-10-28 (FDA).

 

Trade Name

 

Alimta, Armisarte, Pemetrexed Actavis
 

Common Name

 

pemetrexed
 

ChEMBL ID

 

CHEMBL225072
 

Indication

 

mesothelial neoplasms, mesothelioma, non-small-cell lung carcinoma
 

Drug Class

 

Antineoplastic thymidylate synthetase inhibitors

Image (chem structure or protein)

Pemetrexed structure rendering