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Oteracil
Teysuno (oteracil) is a small molecule pharmaceutical. Oteracil was first approved as Teysuno on 2011-03-14. It has been approved in Europe to treat stomach neoplasms.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
digestive system diseasesD004066
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
45 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Stomach neoplasmsD013274EFO_0003897C1611212123
Colorectal neoplasmsD015179134
Head and neck neoplasmsD006258112
AdenocarcinomaD000230112
Neoplasm metastasisD009362EFO_000970811
Adjuvant chemotherapyD01702411
CarcinomaD002277C80.011
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pancreatic neoplasmsD010190EFO_0003860C2533
NeoplasmsD009369C80123
Breast neoplasmsD001943EFO_0003869C5022
Squamous cell carcinoma of head and neckD00007719522
Gastrointestinal neoplasmsD005770C26.911
Bile duct neoplasmsD00165011
Pancreatic ductal carcinomaD02144111
Drug therapyD004358111
Uterine cervical neoplasmsD002583111
Nasopharyngeal neoplasmsD00930311
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Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOTERACIL
INNoteracil
Description
Tegafur/gimeracil/oteracil, sold under the brand name Teysuno among others is a fixed-dose combination medication used for the treatment of advanced gastric cancer when used in combination with cisplatin, and also for the treatment of head and neck cancer, colorectal cancer, non–small-cell lung, breast, pancreatic, and biliary tract cancers.: 213 
Classification
Small molecule
Drug classuracil type antineoplastics
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(O)c1nc(=O)[nH]c(=O)[nH]1
Identifiers
PDB
CAS-ID937-13-3
RxCUI
ChEMBL IDCHEMBL181932
ChEBI ID30863
PubChem CID54715158
DrugBankDB03209
UNII ID5VT6420TIG (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,615 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,657 adverse events reported
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