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Nafcillin
Nallpen (nafcillin) is a small molecule pharmaceutical. Nafcillin was first approved as Unipen on 1982-01-01. It is used to treat bacterial endocarditis, bacterial infections, bacterial meningitis, bacterial skin diseases, and cellulitis amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Nallpen (generic drugs available since 2011-04-20, discontinued: Unipen)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Nafcillin sodium
Tradename
Company
Number
Date
Products
NALLPEN IN PLASTIC CONTAINERBaxterN-050655 RX1989-10-31
2 products, RLD, RS
Show 6 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
nafcillinANDA2023-02-14
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial endocarditisEFO_1000830D004697—
bacterial infections—D001424A49
bacterial meningitisEFO_1000831D016920G00
bacterial skin diseases—D017192—
cellulitisEFO_0003035D002481L03.90
osteomyelitisEFO_0003102D010019M86
postoperative complications—D011183—
respiratory tract infections—D012141J06.9
staphylococcal infections—D013203A49.01
urinary tract infectionsEFO_0003103D014552N39.0
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CF: Beta-lactamase resistant penicillins
— J01CF06: Nafcillin
HCPCS
Code
Description
S0032
Injection, nafcillin sodium, 2 grams
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Neonatal sepsisD000071074HP_0040187————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNAFCILLIN
INNnafcillin
Description
Nafcillin is a penicillin in which the substituent at position 6 of the penam ring is a (2-ethoxy-1-naphthoyl)amino group. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a nafcillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOc1ccc2ccccc2c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12
Identifiers
PDB—
CAS-ID147-52-4
RxCUI7233
ChEMBL IDCHEMBL1443
ChEBI ID7447
PubChem CID8982
DrugBankDB00607
UNII ID4CNZ27M7RV (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 3,061 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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20 adverse events reported
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