Methacycline
Rondomycin (methacycline) is a small molecule pharmaceutical. Methacycline was first approved as Rondomycin on 1982-01-01.
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Indications
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Clinical
Clinical Trials
45 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 1 | 1 | 5 | 5 | 19 | 31 |
| Cough | D003371 | HP_0012735 | R05 | — | — | — | 1 | 1 | 2 |
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bronchial hyperreactivity | D016535 | — | — | — | — | 4 | 4 | ||
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 2 | 2 |
| Exercise-induced asthma | D001250 | J45.990 | — | — | — | — | 2 | 2 | |
| Allergic rhinitis | D065631 | J30.9 | — | — | — | — | 1 | 1 | |
| Hypophosphatemic rickets | D063730 | E83.31 | — | — | — | — | 1 | 1 | |
| Dyspnea | D004417 | HP_0002094 | R06.0 | — | — | — | — | 1 | 1 |
| Hiv | D006678 | O98.7 | — | — | — | — | 1 | 1 | |
| Adiposity | D050154 | — | — | — | — | 1 | 1 | ||
| Respiratory hypersensitivity | D012130 | — | — | — | — | 1 | 1 | ||
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | METHACYCLINE |
| INN | metacycline |
| Description | Metacycline or methacycline is a tetracycline antibiotic. It is used as a precursor in the industrial synthesis of doxycycline hyclate.
|
| Classification | Small molecule |
| Drug class | antibiotics (tetracycline derivatives) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | C=C1c2cccc(O)c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12 |
Identifiers
| PDB | — |
| CAS-ID | 914-00-1 |
| RxCUI | 6812 |
| ChEMBL ID | CHEMBL249837 |
| ChEBI ID | 6805 |
| PubChem CID | 5281054 |
| DrugBank | DB00931 |
| UNII ID | IR235I7C5P (ChemIDplus, GSRS) |
Target
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Variants
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Additional graphs summarizing 346 documents
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Safety
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Adverse Events
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38 adverse events reported
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