Skip to content
Reblozyl(luspatercept)
Reblozyl (luspatercept) is a protein pharmaceutical. Luspatercept was first approved as Reblozyl on 2019-11-08. It is used to treat anemia in the USA. It has been approved in Europe to treat anemia, beta-thalassemia, and myelodysplastic syndromes. It is known to target growth/differentiation factor 11, bone morphogenetic protein 10, growth/differentiation factor 2, growth/differentiation factor 8, and bone morphogenetic protein 6.
Download report
Favorite
BMS
FDA Novel Drug Approvals 2019
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
hemic and lymphatic diseasesD006425
hereditary congenital and neonatal diseases and abnormalitiesD009358
Trade Name
FDA
EMA
Reblozyl
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Luspatercept
Tradename
Proper name
Company
Number
Date
Products
Reblozylluspatercept-aamtCelgeneN-761136 RX2019-11-08
2 products
Labels
FDA
EMA
Brand Name
Status
Last Update
reblozylBiologic Licensing Application2020-10-16
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
anemiaEFO_0004272D000740D64.9
Agency Specific
FDA
EMA
Expiration
Code
luspatercept, Reblozyl, Celgene Corporation, a Bristol-Myers Squibb Company
2027-04-03Orphan excl.
Patent Expiration
No data
ATC Codes
B: Blood and blood forming organ drugs
B03: Antianemic preparations
B03X: Other antianemic preparations in atc
B03XA: Other antianemic preparations in atc
B03XA06: Luspatercept
HCPCS
Code
Description
J0896
Injection, luspatercept-aamt, 0.25 mg
Clinical
Clinical Trials
27 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Beta-thalassemiaD017086Orphanet_848D56.13216
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myelodysplastic syndromesD009190D4626410
AnemiaD000740EFO_0004272D64.91416
Primary myelofibrosisD055728D47.4112
Erythrocyte transfusionD01770711
Myeloproliferative disordersD009196D47.111
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ThalassemiaD013789EFO_1001996D5611
Alpha-thalassemiaD017085Orphanet_846D56.011
ThrombocytosisD013922D75.8311
Aplastic anemiaD000741HP_0001915D61.911
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameLUSPATERCEPT
INNluspatercept
Description
Luspatercept
Classification
Protein
Drug classreceptor molecules or membrane ligands, natural, modified or modified: transforming growth factor receptors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID1373715-00-4
RxCUI2262544
ChEMBL IDCHEMBL3039545
ChEBI ID
PubChem CID
DrugBankDB12281
UNII IDAQK7UBA1LS (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
GDF11
GDF11
BMP10
BMP10
GDF2
GDF2
MSTN
MSTN
BMP6
BMP6
Organism
Homo sapiens
Gene name
GDF11
Gene synonyms
BMP11
NCBI Gene ID
Protein name
growth/differentiation factor 11
Protein synonyms
BMP-11, Bone morphogenetic protein 11, GDF-11
Uniprot ID
Mouse ortholog
Gdf11 (14561)
growth/differentiation factor 11 (Q9Z1W4)
Variants
Clinical Variant
No data
Financial
Reblozyl - Bristol Myers Squibb
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Reblozyl - Merck Sharp & Dohme
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 473 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
171 adverse events reported
View more details