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Ingenol mebutate

Picato (ingenol mebutate) is a small molecule pharmaceutical. Ingenol mebutate was first approved as Picato on 2012-01-23. It is used to treat actinic keratosis in the USA. The pharmaceutical is active against protein kinase C delta type. In addition, it is known to target protein kinase C epsilon type, protein kinase C alpha type, protein kinase C gamma type, and protein kinase C beta type. Picato’s patents are valid until 2033-05-15 (FDA).


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Common Name


ingenol mebutate






actinic keratosis

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Image (chem structure or protein)

Ingenol mebutate structure rendering