Hypromellose
Hypromellose is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| eye diseases | D005128 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| bion tears | OTC monograph final | 2023-05-18 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
145 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dry eye syndromes | D015352 | H04.12 | 2 | 5 | 7 | 17 | 20 | 50 | |
| Glaucoma | D005901 | EFO_0000516 | H40 | 1 | 1 | — | 5 | 4 | 11 |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | 1 | — | 9 | — | 10 |
| Ocular hypertension | D009798 | EFO_1001069 | H40.0 | — | 1 | — | 6 | — | 7 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 2 | 4 | 6 |
| Meibomian gland dysfunction | D000080343 | H02.88 | — | — | — | 2 | 4 | 6 | |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | 1 | 2 | 1 | 4 |
| Intraocular pressure | D007429 | — | — | — | 1 | 2 | 3 | ||
| Keratoconjunctivitis sicca | D007638 | EFO_1000906 | — | — | — | 1 | 1 | 2 | |
| Macular edema | D008269 | — | 1 | 1 | 1 | — | 2 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type c niemann-pick disease | D052556 | Orphanet_646 | E75.242 | 4 | 2 | 1 | — | — | 5 |
| Viral conjunctivitis | D003236 | EFO_0008571 | B30 | — | 1 | 2 | — | 1 | 3 |
| Keratitis | D007634 | H16 | — | 2 | 2 | — | 1 | 3 | |
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | 1 | 1 | — | 1 | 2 |
| Acanthamoeba keratitis | D015823 | EFO_0007126 | — | 1 | 1 | — | — | 2 | |
| Trichiasis | D058457 | HP_0001128 | — | — | 1 | — | 1 | 2 | |
| Eye diseases | D005128 | EFO_0003966 | H44 | — | — | 1 | — | 1 | 2 |
| Wet macular degeneration | D057135 | EFO_0004683 | — | 1 | 1 | — | — | 1 | |
| Healthy volunteers/patients | — | — | — | 1 | — | — | 1 | ||
| Exfoliation syndrome | D017889 | EFO_0004235 | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Herpes zoster | D006562 | EFO_0006510 | B02 | — | 1 | — | — | — | 1 |
| Thyroid neoplasms | D013964 | EFO_0003841 | — | 1 | — | — | — | 1 | |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cataract | D002386 | EFO_0001059 | H26.9 | 1 | — | — | — | 2 | 3 |
| Diabetic retinopathy | D003930 | EFO_0003770 | 1 | — | — | — | — | 1 | |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
| Sturge-weber syndrome | D013341 | Orphanet_3205 | Q85.89 | 1 | — | — | — | — | 1 |
| Port-wine stain | D019339 | Q82.5 | 1 | — | — | — | — | 1 | |
| Hyperemia | D006940 | EFO_0003822 | H34.82 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | — | — | — | — | 2 | 2 |
| Strabismus | D013285 | HP_0000486 | H50.2 | — | — | — | — | 1 | 1 |
| Adenoviridae infections | D000257 | EFO_1001259 | B34.0 | — | — | — | — | 1 | 1 |
| Corneal diseases | D003316 | H18.9 | — | — | — | — | 1 | 1 | |
| Conjunctivitis | D003231 | H10 | — | — | — | — | 1 | 1 | |
| Trachoma | D014141 | A71 | — | — | — | — | 1 | 1 | |
| Microbiota | D064307 | — | — | — | — | 1 | 1 | ||
| Blepharitis | D001762 | EFO_0009536 | H01.0 | — | — | — | — | 1 | 1 |
| Eye pain | D058447 | HP_0200026 | H57.1 | — | — | — | — | 1 | 1 |
| Myopia | D009216 | H52.1 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | HYPROMELLOSE |
| INN | hypromellose |
| Description | Hypromellose (INN), short for hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, viscoelastic polymer used in eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 9004-65-3 |
| RxCUI | 27334 |
| ChEMBL ID | CHEMBL2108956 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB11075 |
| UNII ID | 3NXW29V3WO (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,144 adverse events reported
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