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Hydrocortamate
Magnacort (hydrocortamate) is a small molecule pharmaceutical. Hydrocortamate was first approved as Magnacort on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Hydrocortamate hydrochloride
Tradename
Company
Number
Date
Products
MAGNACORTMylanN-010554 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
84 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PainD010146EFO_0003843R524755223
Postoperative painD010149G89.18——1416
Chronic painD059350HP_0012532——32—5
Postoperative nausea and vomitingD020250EFO_0004888———112
Rotator cuff injuriesD000070636M75.1—1—1—2
Pain managementD059408———2—2
ToothacheD014098K08.89———112
Rib fracturesD012253———1—1
Colonic neoplasmsD003110C18———1—1
Rectal neoplasmsD012004———1—1
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Low back painD017116HP_0003419M54.5—14—16
OsteoarthritisD010003EFO_0002506M15-M19—11——2
Anterior cruciate ligament injuriesD000070598—11——1
Shoulder painD020069HP_0030834M25.51——1——1
Multiple myelomaD009101C90.0——1——1
LymphomaD008223C85.9——1——1
Head and neck neoplasmsD006258——1——1
MucositisD052016EFO_1001898——1——1
VomitingD014839HP_0002013R11.1——1——1
NauseaD009325HP_0002018R11.0——1——1
Show 4 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Musculoskeletal painD05935211———2
Corneal injuriesD065306HP_0000559—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—5————5
Drug interactionsD0043471———12
Ankle fracturesD064386S82.51————1
Substance-related disordersD019966EFO_0003890F131————1
Hepatic insufficiencyD0485501————1
Renal insufficiencyD051437HP_0000083N191————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C50————11
Corneal diseasesD003316H18.9————11
Acute painD059787R52————11
ThyroidectomyD013965————11
Soft tissue injuriesD017695————11
LacerationsD022125————11
MethodsD008722————11
Tooth migrationD014085————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameHYDROCORTAMATE
INNhydrocortamate
Description
Hydrocortamate is a glycinyl ester, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a glucocorticoid, a 3-oxo-Delta(4) steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug and an immunosuppressive agent. It is functionally related to a cortisone.
Classification
Small molecule
Drug classcortisone derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCN(CC)CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
Identifiers
PDB—
CAS-ID76-47-1
RxCUI—
ChEMBL IDCHEMBL1201263
ChEBI ID50851
PubChem CID84088
DrugBankDB00769
UNII IDY3N00BK5WK (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 8 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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246 adverse events reported
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