In the BioHarmony Drug Report Database

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Fedratinib

Inrebic (fedratinib) is a small molecule pharmaceutical. Fedratinib was first approved as Inrebic on 2019-08-16. It is used to treat primary myelofibrosis in the USA. It has been approved in Europe to treat myeloproliferative disorders and primary myelofibrosis. The pharmaceutical is active against tyrosine-protein kinase JAK2. In addition, it is known to target tyrosine-protein kinase JAK1, tyrosine-protein kinase JAK3, bromodomain-containing protein 4, and non-receptor tyrosine-protein kinase TYK2. Inrebic’s patents are valid until 2032-06-04 (FDA).

 

Trade Name

 

Inrebic
 

Common Name

 

fedratinib
 

ChEMBL ID

 

CHEMBL1287853
 

Indication

 

myeloproliferative disorders, primary myelofibrosis
 

Drug Class

 

Tyrosine kinase inhibitors

Image (chem structure or protein)

Fedratinib structure rendering