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Ethionamide
Trecator (ethionamide) is a small molecule pharmaceutical. Ethionamide was first approved as Trecator on 1982-01-01. It is used to treat mycobacterium infections and tuberculosis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
Trecator
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ethionamide
Tradename
Company
Number
Date
Products
TRECATORWYETH PHARMSN-013026 RX1982-01-01
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
trecatorNew Drug Application2020-07-23
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
mycobacterium infections—D009164A31.9
tuberculosisEFO_0000774D014376A15-A19
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J04: Antimycobacterials
— J04A: Drugs for treatment of tuberculosis
— J04AD: Thiocarbamide derivatives for treatment of tuberculosis
— J04AD03: Ethionamide
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameETHIONAMIDE
INNethionamide
Description
Ethionamide is a thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide. It has a role as an antitubercular agent, an antilipemic drug, a fatty acid synthesis inhibitor, a leprostatic drug and a prodrug. It is a member of pyridines and a thiocarboxamide.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCc1cc(C(N)=S)ccn1
Identifiers
PDB—
CAS-ID536-33-4
RxCUI4127
ChEMBL IDCHEMBL1441
ChEBI ID4885
PubChem CID2761171
DrugBankDB00609
UNII IDOAY8ORS3CQ (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 3,811 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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