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Ripretinib

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Qinlock (ripretinib) is a small molecule pharmaceutical. Ripretinib was first approved as Qinlock on 2020-05-15. It is used to treat gastrointestinal stromal tumors in the USA. The pharmaceutical is active against mast/stem cell growth factor receptor Kit and platelet-derived growth factor receptor alpha. Qinlock’s patents are valid until 2040-08-12 (FDA).

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Trade Name

 Qinlock

Common Name

 ripretinib

ChEMBL ID

 CHEMBL4216467

Indication

 gastrointestinal stromal tumors

Drug Class

 Retinol derivatives; tyrosine kinase inhibitors

Image (chem structure or protein)

Ripretinib structure rendering

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Every Drug Dataset Includes...

Full Drug Information

Including:

Trade name (FDA, EMA)

Drug common name

Description

Classification

Drug class

Image (chemical or protein structure)

Protein Data Bank ID

Structure (InChI/SMILES or Protein Sequence)

CAS-ID

RxCUI

ChEMBL ID

ChEBI ID

PubChem CID

DrugBank ID

Indications

Including:

Agency approved indications

Phase 1 Indications

Phase 2 Indications

Phase 3 Indications

Phase 4 Indications

MeSH identifiers

Ontology identifiers

Target Information

Including:

Agency Approved Targets

Alternative Targets

Gene name

Gene synonyms

NCBI Gene ID

Protein name

Protein synonyms

Uniprot ID

Orthologs

Clinical Variant Information

Including:

ClinVar ID

Target mutation

Effect

Evaluation date

PharmGKB level

Clinical Trial Information

Including:

NCT ID

Trial Timeline

Results

Phase

Expanded Access

Official Title

Sponsor

Indications / Phase Indications

Study Type

Enrollment

Inclusion Criteria

Exclusion Criteria

Links to Clinical Trials

Reimbursement Codes

Including:

ICD-10

ATC

HCPCS

Safety Information

Including:

Black Box Warnings

Adverse Events

Adverse Reactions

Expedite Criteria

Trend Information

Including:

Top, trending, and new metadata terms in the following categories:

Disease or Syndrome

Pharmacological Substances

Biological Entities

Laboratory Procedures

Commercial Information

Including:

Company (FDA, EMA)

Approval Date (FDA, EMA)

Exclusivity

Patent Expiration

Generics and Biosimilars (FDA, EMA)

Drug Labels

Economic Information

Including:

Company

Annual revenue

Quarterly revenue

Global sales

US sales

Non-US sales

Full dataset compatible with-

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Spotfire & Tableau for visualization
<strong>CSV</strong> export file format
CSV export file format
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JSON export file format
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XLSX export file format

Continually updated information available as a yearly subscription for individual drug-of-interest.

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