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Pemetrexed

Pemetrexed, Pemfexy, Alimta, Armisarte, Pemetrexed Actavis (pemetrexed) is a small molecule pharmaceutical. Pemetrexed was first approved as Pemetrexed on 2004-09-20. It is used to treat mesothelial neoplasms and non-small-cell lung carcinoma in the USA. It has been approved in Europe to treat mesothelioma and non-small-cell lung carcinoma. The pharmaceutical is active against dihydrofolate reductase. In addition, it is known to target thymidylate synthase, proton-coupled folate transporter, and trifunctional purine biosynthetic protein adenosine-3. Alimta’s patents are valid until 2035-10-28 (FDA).

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Trade Name

Alimta, Armisarte, Pemetrexed Actavis

Common Name

pemetrexed

ChEMBL ID

CHEMBL225072

Indication

mesothelial neoplasms, mesothelioma, non-small-cell lung carcinoma

Drug Class

Antineoplastic thymidylate synthetase inhibitors

Image (chem structure or protein)

Pemetrexed structure rendering

$325 / month$3,000 / year

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Protein Data Bank ID

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RxCUI

ChEMBL ID

ChEBI ID

PubChem CID

DrugBank ID

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Agency approved indications

Phase 1 Indications

Phase 2 Indications

Phase 3 Indications

Phase 4 Indications

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Ontology identifiers

Target Information

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Agency Approved Targets

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Gene name

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NCBI Gene ID

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Uniprot ID

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Clinical Variant Information

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ClinVar ID

Target mutation

Effect

Evaluation date

PharmGKB level

Clinical Trial Information

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NCT ID

Trial Timeline

Results

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Expanded Access

Official Title

Sponsor

Indications / Phase Indications

Study Type

Enrollment

Inclusion Criteria

Exclusion Criteria

Links to Clinical Trials

Reimbursement Codes

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HCPCS

Safety Information

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Black Box Warnings

Adverse Events

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Trend Information

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Top, trending, and new metadata terms in the following categories:

Disease or Syndrome

Pharmacological Substances

Biological Entities

Laboratory Procedures

Commercial Information

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Company (FDA, EMA)

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Exclusivity

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