Ritodrine
Yutopar (ritodrine) is a small molecule pharmaceutical. Ritodrine was first approved as Yutopar on 1982-01-01.
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Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
93 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | 4 | 1 | 15 | 10 | 6 | 35 |
| Postmenopausal osteoporosis | D015663 | EFO_0003854 | — | 2 | 9 | 11 | 1 | 23 | |
| Metabolic bone diseases | D001851 | HP_0000938 | 2 | — | 3 | 1 | 2 | 8 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | 4 | 2 | — | 6 |
| Prostatic neoplasms | D011471 | C61 | — | — | 3 | 1 | — | 4 | |
| Osteogenesis imperfecta | D010013 | Q78.0 | — | 1 | 1 | 1 | — | 3 | |
| Colles' fracture | D003100 | S52.53 | — | — | — | 1 | — | 1 | |
| Femoral neck fractures | D005265 | EFO_1001792 | S72.00 | — | — | — | 1 | — | 1 |
| Osteoporotic fractures | D058866 | — | — | — | 1 | — | 1 | ||
| Weight loss | D015431 | HP_0001824 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteitis deformans | D010001 | EFO_0004261 | M88 | — | — | 2 | — | 1 | 3 |
| Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | — | 1 | 1 | — | 1 | 2 |
| Back pain | D001416 | HP_0003418 | M54 | — | — | 1 | — | — | 1 |
| Spinal fractures | D016103 | EFO_0003902 | S12 | — | — | 1 | — | — | 1 |
| Menopause | D008593 | EFO_0003922 | N95 | — | — | 1 | — | — | 1 |
| Leukemia | D007938 | C95 | — | — | 1 | — | — | 1 | |
| Lymphoma | D008223 | C85.9 | — | — | 1 | — | — | 1 | |
| Fibrous dysplasia of bone | D005357 | Orphanet_249 | M27.8 | — | 1 | 1 | — | — | 1 |
| Prosthesis failure | D011475 | — | — | 1 | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 | ||
| Biological availability | D001682 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal neoplasms | D004938 | C15 | — | — | — | — | 1 | 1 | |
| Adenocarcinoma | D000230 | — | — | — | — | 1 | 1 | ||
| Squamous cell neoplasms | D018307 | — | — | — | — | 1 | 1 | ||
| Hip fractures | D006620 | EFO_0003964 | S72.00 | — | — | — | — | 1 | 1 |
| Hyperparathyroidism | D006961 | EFO_0008506 | E21.3 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | RITODRINE |
| INN | ritodrine |
| Description | Ritodrine (trade name Yutopar) is a tocolytic drug used to stop premature labor. This drug has been removed from the US market, according to FDA Orange Book. It was available in oral tablets or as an injection and was typically used as the hydrochloride salt, ritodrine hydrochloride.
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| Classification | Small molecule |
| Drug class | sympathomimetics |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(NCCc1ccc(O)cc1)C(O)c1ccc(O)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 26652-09-5 |
| RxCUI | 9392 |
| ChEMBL ID | CHEMBL83063 |
| ChEBI ID | — |
| PubChem CID | 33572 |
| DrugBank | DB00867 |
| UNII ID | I0Q6O6740J (ChemIDplus, GSRS) |
Target
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Variants
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Safety
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Adverse Events
Top Adverse Reactions
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11,396 adverse events reported
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