Skip to content
Quinupristin
Synercid (quinupristin) is a small molecule pharmaceutical. Quinupristin was first approved as Synercid on 1999-09-21. It is used to treat bacterial infections, staphylococcal infections, and streptococcal infections in the USA.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
Combinations
Synercid
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dalfopristin
+
Quinupristin
Tradename
Company
Number
Date
Products
SYNERCIDKing PharmaceuticalsN-050748 RX1999-09-21
1 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
synercidNew Drug Application2019-08-07
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infectionsD001424A49
staphylococcal infectionsD013203A49.01
streptococcal infectionsEFO_1001476D013290
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01F: Macrolides, lincosamides and streptogramins
J01FG: Streptogramins
J01FG02: Quinupristin/dalfopristin
HCPCS
Code
Description
J2770
Injection, quinupristin/dalfopristin, 500 mg (150/350)
Clinical
Clinical Trials
39 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pseudobulbar palsyD020828EFO_1001131134
Alzheimer diseaseD000544EFO_0000249F031113
StrokeD020521EFO_0000712I63.9112
Traumatic brain injuriesD000070642S06112
Atrial fibrillationD001281EFO_0000275I48.0112
DementiaD003704F0311
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiac arrhythmiasD001145EFO_0004269I49.9144
Amyotrophic lateral sclerosisD000690EFO_0000253G12.211213
Cardiovascular diseasesD002318EFO_0000319I9833
Heart diseasesD006331EFO_0003777I51.933
Parkinson diseaseD010300EFO_0002508G20112
Multiple sclerosisD009103EFO_0003885G35112
Ventricular fibrillationD014693EFO_0004287I49.0122
Huntington diseaseD006816G1011
Myocardial infarctionD009203EFO_0000612I2111
Heart arrestD006323EFO_0009492I4611
Show 2 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Major depressive disorderD003865EFO_0003761F22112
Migraine disordersD008881EFO_0003821G4311
Treatment-resistant depressive disorderD06121811
DyskinesiasD020820G2411
Autistic disorderD001321EFO_0003758F84.011
NeuralgiaD009437EFO_000943011
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients88
Hepatitis bD00650911
Non-alcoholic fatty liver diseaseD065626EFO_0003095K75.8111
ConstipationD003248HP_0002019K59.011
Covid-19D000086382U07.111
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameQUINUPRISTIN
INNquinupristin
Description
Quinupristin is a streptogramin B antibiotic, used in combination with dalfopristin under the trade name Synercid. It has activity against Gram-positive and atypical bacteria but not Gram-negative bacteria. It inhibits bacterial protein synthesis. The combination of quinupristin and dalfopristin is not active against Enterococcus faecalis and needs to be given in combination with other antibacterials for mixed infections that involve Gram-negative organisms.
Classification
Small molecule
Drug classsteriodal compounds acting on progesterone receptors (excluding-gest- compounds); antibacterials, pristinamycin derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2CC(=O)[C@H](CS[C@@H]3CN4CCC3CC4)CN2C(=O)[C@H](Cc2ccc(N(C)C)cc2)N(C)C(=O)[C@@H]2CCCN2C1=O
Identifiers
PDB
CAS-ID120138-50-3
RxCUI229367
ChEMBL IDCHEMBL1200649
ChEBI ID
PubChem CID5388937
DrugBankDB01369
UNII ID23OW28RS7P (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 2,947 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
3,802 adverse events reported
View more details