Alora, Climara, Divigel, Elestrin, Esclim, Estraderm, Estradiol, Estring, Estrogel, Evamist, Fempatch, Imvexxy, Menostar, Minivelle, Vagifem, Vivelle, Vivelle-dot, Zoely (estradiol) is a small molecule pharmaceutical. Estradiol was first approved as Alora on 1986-09-10. It is used to treat breast neoplasms, hot flashes, hypogonadism, menorrhagia, and premature menopause amongst others in the USA. It has been approved in Europe to treat contraception. It is known to target G-protein coupled estrogen receptor 1, estrogen receptor beta, estrogen receptor, Calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel subunit alpha-1, and nuclear receptor subfamily 1 group I member 2. Depo-estradiol's patents are valid until 2033-12-20 (FDA).
|Indication||breast neoplasms, contraception, hot flashes, hypogonadism, menorrhagia, premature menopause, primary ovarian insufficiency, prostatic neoplasms|