Cloxacillin
Cloxapen, Tegopen (cloxacillin) is a small molecule pharmaceutical. Cloxacillin was first approved as Tegopen on 1982-01-01. It is used to treat bacterial pneumonia, cellulitis, joint diseases, osteomyelitis, and postoperative complications amongst others in the USA.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cloxacillin sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| TEGOPEN | Bristol Myers Squibb | N-050192 DISCN | 1982-01-01 | 1 products |
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Indications
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Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| bacterial pneumonia | EFO_1001272 | D018410 | J15.9 |
| cellulitis | EFO_0003035 | D002481 | L03.90 |
| joint diseases | HP_0003040 | D007592 | M12.9 |
| osteomyelitis | EFO_0003102 | D010019 | M86 |
| postoperative complications | — | D011183 | — |
| staphylococcal skin infections | EFO_1001849 | D013207 | L00 |
| urinary tract infections | EFO_0003103 | D014552 | N39.0 |
| wound infection | — | D014946 | — |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Migraine disorders | D008881 | EFO_0003821 | G43 | — | — | 1 | — | — | 1 |
| Headache | D006261 | HP_0002315 | R51 | — | — | 1 | — | — | 1 |
| Migraine without aura | D020326 | EFO_0005296 | G43.0 | — | — | 1 | — | — | 1 |
| Migraine with aura | D020325 | EFO_0005295 | G43.1 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CLOXACILLIN |
| INN | cloxacillin |
| Description | Cloxacillin is a semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6. It has a role as an antibacterial agent and an antibacterial drug. It is a semisynthetic derivative, a penicillin allergen and a penicillin. It is functionally related to an oxacillin. It is a conjugate acid of a cloxacillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12 |
Identifiers
| PDB | — |
| CAS-ID | 61-72-3 |
| RxCUI | 2625 |
| ChEMBL ID | CHEMBL891 |
| ChEBI ID | 49566 |
| PubChem CID | 6098 |
| DrugBank | DB01147 |
| UNII ID | O6X5QGC2VB (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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2,150 adverse events reported
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