Clolar, Evoltra (clofarabine) is a small molecule pharmaceutical. Clofarabine was first approved as Clolar on 2004-12-28. It is used to treat lymphoid leukemia in the USA. It has been approved in Europe to treat precursor cell lymphoblastic leukemia-lymphoma. The pharmaceutical is active against ribonucleoside-diphosphate reductase subunit M2. In addition, it is known to target ribonucleoside-diphosphate reductase large subunit and deoxycytidine kinase.
|Indication||lymphoid leukemia, precursor cell lymphoblastic leukemia-lymphoma|
|Drug Class||Antineoplastics (arabinofuranosyl derivatives)|