Skip to content
Elspar, Spectrila(asparaginase)
Elspar, Spectrila (asparaginase) is an enzyme pharmaceutical. Asparaginase was first approved as Elspar on 1978-01-10. It is used to treat cholelithiasis, lymphoma, and precursor cell lymphoblastic leukemia-lymphoma in the USA. It has been approved in Europe to treat precursor cell lymphoblastic leukemia-lymphoma.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
digestive system diseasesD004066
hemic and lymphatic diseasesD006425
immune system diseasesD007154
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Asparaginase
Tradename
Proper name
Company
Number
Date
Products
ElsparasparaginaseRecordati Rare Diseases, Inc.N-101063 DISCN1978-01-10
1 products
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
cholelithiasisEFO_0004799D002769K80
lymphomaD008223C85.9
precursor cell lymphoblastic leukemia-lymphomaD054198C91.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
L01: Antineoplastic agents
L01X: Other antineoplastic agents in atc
L01XX: Other antineoplastic agents in atc
L01XX02: Asparaginase
HCPCS
Code
Description
J9019
Injection, asparaginase (erwinaze), 1,000 iu
J9020
Injection, asparaginase, not otherwise specified, 10,000 units
J9021
Injection, asparaginase, recombinant, (rylaze), 0.1 mg
Clinical
Clinical Trials
175 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.0183826141196
T-cell lymphoma peripheralD016411C84.911
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938C9522021547
LymphomaD008223C85.96713
Myeloid leukemia acuteD015470C92.014611
Myelodysplastic syndromesD009190D461157
Non-hodgkin lymphomaD008228C85.91315
Down syndromeD004314EFO_0001064Q90123
Megakaryoblastic leukemia acuteD007947C94.222
Monocytic leukemia acuteD00794822
Myelomonocytic leukemia acuteD015479C92.522
Erythroblastic leukemia acuteD004915EFO_1001257C94.022
Show 9 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
T-cell lymphomaD0163992114
Biphenotypic leukemia acuteD015456C95.0144
Extranodal nk-t-cell lymphomaD054391C86.0112
Philadelphia chromosomeD010677212
Precursor t-cell lymphoblastic leukemia-lymphomaD054218112
Hematologic neoplasmsD019337112
Inborn genetic diseasesD030342EFO_000050811
T-cell leukemiaD01545811
B-cell leukemiaD01544811
NeutropeniaD009503D7011
Show 3 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypersensitivityD006967EFO_0003785T78.4011
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ataxia telangiectasiaD001260Orphanet_100G11.311
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameASPARAGINASE
INNcrisantaspase
Description
Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). It is given by injection into a vein, muscle, or under the skin. A pegylated version is also available. In food manufacturing it is used to decrease acrylamide.
Classification
Enzyme
Drug classenzymes
Image (chem structure or protein)ASPARAGINASE
Structure (InChI/SMILES or Protein Sequence)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 10,351 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
177 adverse events reported
View more details