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Doribax(doripenem)
Doribax (doripenem) is a small molecule pharmaceutical. Doripenem was first approved as Doribax on 2007-10-12. It is used to treat bacterial infections, intraabdominal infections, and urinary tract infections in the USA. It has been approved in Europe to treat bacterial infections, bacterial pneumonia, cross infection, urinary tract infections, and ventilator-associated pneumonia.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
urogenital diseasesD000091642
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Doripenem
Tradename
Company
Number
Date
Products
DORIBAXShionogiN-022106 DISCN2007-10-12
2 products, RLD
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infectionsD001424A49
intraabdominal infectionsD059413
urinary tract infectionsEFO_0003103D014552N39.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01D: Other beta-lactam antibacterials in atc
J01DH: Carbapenems
J01DH04: Doripenem
HCPCS
Code
Description
J1267
Injection, doripenem, 10 mg
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atrial fibrillationD001281EFO_0000275I48.01124
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PharmacokineticsD01059922
Long qt syndromeD008133HP_0001657I45.81112
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Drug-related side effects and adverse reactionsD064420T88.711
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDORIPENEM
INNdoripenem
Description
Doripenem is a member of carbapenems.
Classification
Small molecule
Drug classantibacterial antibiotics, carbapenem derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](CNS(N)(=O)=O)C3)[C@H](C)[C@H]12
Identifiers
PDB
CAS-ID148016-81-3
RxCUI119771
ChEMBL IDCHEMBL491571
ChEBI ID
PubChem CID73303
DrugBankDB06211
UNII IDBHV525JOBH (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,609 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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7,473 adverse events reported
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