Skip to content
Ciprofloxacin
Cetraxal, Ciloxan, Cipro, Ciprodex, Otovel (ciprofloxacin) is a small molecule pharmaceutical. Ciprofloxacin was first approved as Cipro on 1987-10-22. It is used to treat anthrax, bacterial conjunctivitis, bacterial infections, bacterial skin diseases, and bacteroides infections amongst others in the USA.
Download report
Favorite
Novartis Pharmaceuticals
Searched
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
digestive system diseasesD004066
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
eye diseasesD005128
urogenital diseasesD000091642
hemic and lymphatic diseasesD006425
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Cetraxal, Ciloxan, Cipro (generic drugs available since 2004-06-09, discontinued: Otiprio, Proquin)
Combinations
Cipro, Ciprodex, Otovel (generic drugs available since 2004-06-09, discontinued: Cipro)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ciprofloxacin
Tradename
Company
Number
Date
Products
CIPROBayerN-020780 RX1997-09-26
2 products, RLD, RS
Show 4 discontinued
Ciprofloxacin
+
Ciprofloxacin hydrochloride
Tradename
Company
Number
Date
Products
CIPRO XRBayerN-021473 DISCN2002-12-13
2 products
Hide discontinued
Ciprofloxacin
+
Dexamethasone
Tradename
Company
Number
Date
Products
CIPRODEXNovartisN-021537 RX2003-07-18
1 products, RLD, RS
Ciprofloxacin hydrochloride
Tradename
Company
Number
Date
Products
CIPROBayerN-019537 RX1987-10-22
2 products, RLD, RS
CILOXANNovartisN-019992 RX1990-12-31
1 products, RLD, RS
CILOXANNovartisN-020369 RX1998-03-30
1 products, RLD, RS
CETRAXALWraSer PharmaceuticalsN-021918 RX2009-05-01
1 products, RLD, RS
Show 2 discontinued
Ciprofloxacin hydrochloride
+
Fluocinolone acetonide
Tradename
Company
Number
Date
Products
OTOVELLaboratorios SalvatN-208251 RX2016-04-29
1 products, RLD, RS
Ciprofloxacin hydrochloride
+
Hydrocortisone
Tradename
Company
Number
Date
Products
CIPRO HCNovartisN-020805 RX1998-02-10
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
cetraxalNew Drug Application2021-01-30
ciloxanNew Drug Application2022-06-07
ciprodexNew Drug Application2021-10-01
ciprofloxacinANDA2023-06-09
otovelNew Drug Application2021-10-05
proquinNew Drug Application2010-07-06
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
anthraxD000881A22
bacterial conjunctivitisEFO_1000829D003234H10.0
bacterial infectionsD001424A49
bacterial skin diseasesD017192
bacteroides infectionsEFO_1000832D001442
campylobacter infectionsEFO_0007190D002169
cystitisEFO_1000025D003556N30
diarrheaHP_0002014D003967R19.7
dysenteryEFO_1001869D004403
escherichia coli infectionsEFO_1001318D004927B96.20
Show 18 more
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Ciprofloxacin, Otiprio, Alk Abello
112468632038-11-27DP
110400042037-11-12U-2252
92207962035-07-01DP
83188172030-04-27U-1792
92330682029-12-11DP
92050482029-04-21U-1793
96037962029-04-21DS, DPU-2252
113695662029-04-21DP
Ciprofloxacin Hydrochloride / Fluocinolone Acetonide, Otovel, Laboratorios Salvat
89326102030-03-24DPU-1578
Ciprofloxacin / Dexamethasone, Ciprodex, Novartis
88466502025-06-04DPU-1578
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01M: Quinolone antibacterials
J01MA: Fluoroquinolone antibacterials, systemic
J01MA02: Ciprofloxacin
J01R: Combinations of antibacterials
J01RA: Combinations of antibacterials
J01RA10: Ciprofloxacin and metronidazole
J01RA11: Ciprofloxacin and tinidazole
J01RA12: Ciprofloxacin and ornidazole
S: Sensory organ drugs
S01: Ophthalmologicals
S01A: Antiinfective ophthalmologics
S01AE: Fluoroquinolone antiinfectives, ophthalmologic
S01AE03: Ciprofloxacin
S02: Otologicals
S02A: Antiinfective drugs, otologic
S02AA: Antiinfectives
S02AA15: Ciprofloxacin
S03: Ophthalmological and otological preparations
S03A: Antiinfectives, ophthalmologic and otologic
S03AA: Antiinfectives
S03AA07: Ciprofloxacin
HCPCS
Code
Description
J0744
Injection, ciprofloxacin for intravenous infusion, 200 mg
J7342
Instillation, ciprofloxacin otic suspension, 6 mg
Clinical
Clinical Trials
250 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Urinary tract infectionsD014552EFO_0003103N39.04813429
InfectionsD007239EFO_00005441124310
Cystic fibrosisD003550EFO_0000390E84222129
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9312118
Prostatic neoplasmsD011471C6112216
PyelonephritisD011704EFO_1001141N10-N162114
NeutropeniaD009503D702114
Liver cirrhosisD008103EFO_0001422K74.0213
Breast neoplasmsD001943EFO_0003869C50123
Otitis mediaD010033EFO_0004992H66.9213
Show 31 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Otitis externaD010032EFO_0009560H6014711
Crohn diseaseD003424EFO_0000384K50617
Bacterial infectionsD001424A4931227
BronchiectasisD001987HP_0002110J472215
NeoplasmsD009369C801214
LymphomaD008223C85.91113
PneumoniaD011014EFO_0003106J181113
CholeraD002771A0022
PlagueD010930EFO_0007481A20112
Communicable diseasesD003141112
Show 16 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnthraxD000881A22224
OtitisD010031133
Ear diseasesD004427EFO_1001455H93.9133
Otorhinolaryngologic diseasesD010038133
Amyotrophic lateral sclerosisD000690EFO_0000253G12.21112
Diabetic footD017719EFO_10014591112
Systemic inflammatory response syndromeD018746EFO_1001478R65.10112
LeukemiaD007938C951112
GonorrheaD006069DOID_7551A54112
Hiv infectionsD015658EFO_0000764B2011
Show 15 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients10212
PharmacokineticsD010599213
RhinoscleromaD012226EFO_000747022
Thrombocytopenic purpura idiopathicD016553EFO_0007160D69.311
Pancreatic ductal carcinomaD02144111
Brain injuriesD001930S06.911
Alcoholic liver cirrhosisD008104EFO_1000802K70.311
Alcoholic hepatitisD006519EFO_1001345K70.111
Phase i metabolic detoxicationD05021611
Periapical periodontitisD010485EFO_1001391K04.511
Show 4 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteomyelitisD010019EFO_0003102M8622
PeritonitisD010538EFO_0008588K6522
PregnancyD011247EFO_0002950Z33.111
Chronic bronchitisD029481J4211
Staphylococcus aureusD013211NCBITaxon_128011
Periapical diseasesD010483EFO_001068811
Coronary artery diseaseD003324I25.111
Chronic kidney failureD007676EFO_0003884N18.611
Myelodysplastic syndromesD009190D4611
Myeloproliferative disordersD009196D47.111
Show 15 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameCIPROFLOXACIN
INNciprofloxacin
Description
Ciprofloxacin is a quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. It has a role as an antiinfective agent, a topoisomerase IV inhibitor, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a DNA synthesis inhibitor, an antimicrobial agent, an environmental contaminant and a xenobiotic. It is a quinolone antibiotic, a fluoroquinolone antibiotic, a member of cyclopropanes, a N-arylpiperazine, a quinolone, an aminoquinoline and a quinolinemonocarboxylic acid. It is a conjugate base of a ciprofloxacin(1+). It is a tautomer of a ciprofloxacin zwitterion.
Classification
Small molecule
Drug classantibacterials (quinolone derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
Identifiers
PDB
CAS-ID85721-33-1
RxCUI2551
ChEMBL IDCHEMBL8
ChEBI ID100241
PubChem CID2764
DrugBankDB00537
UNII ID5E8K9I0O4U (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,774 documents
View more details
Safety
Black-box Warning
Black-box warning for: Ciprofloxacin, Proquin
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
2,290 adverse events reported
View more details