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Chloroxine
Capitrol (chloroxine) is a small molecule pharmaceutical. Chloroxine was first approved as Capitrol on 1982-01-01. It is used to treat scalp dermatoses and seborrheic dermatitis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Chloroxine
Tradename
Company
Number
Date
Products
CAPITROLWestwood-Squibb PharmaceuticalsN-017594 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
scalp dermatosesD012536
seborrheic dermatitisD012628L21
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
267 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver neoplasmsD008113EFO_1001513C22.01171541466192
Hepatocellular carcinomaD006528C22.0517321135
Colorectal neoplasmsD0151792114
Neoplasm metastasisD009362EFO_00097081213
ThrombosisD013927112
Circulating neoplastic cellsD009360112
Therapeutic chemoembolizationD01646111
Ablation techniquesD05501111
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ImmunotherapyD007167112
Colonic neoplasmsD003110C18111
Germ cell and embryonal neoplasmsD00937311
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CholangiocarcinomaD018281C22.1718
NeoplasmsD009369C8033
Digestive system neoplasmsD00406733
Biliary tract neoplasmsD001661C24.9122
Liver diseasesD008107EFO_0001421K70-K7722
Bile duct neoplasmsD00165011
AdenocarcinomaD00023011
Neoplasms by histologic typeD00937011
Neoplasms by siteD00937111
Glandular and epithelial neoplasmsD00937511
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Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Portal hypertensionD006975EFO_0000666K76.622
Molecular targeted therapyD05899011
Liver failureD017093HP_0001399K72.911
Survival rateD01599611
Liver transplantationD016031EFO_001068211
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCHLOROXINE
INN
Description
Chloroxine is a monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. A synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp. It has a role as an antibacterial agent, an antiseborrheic and an antifungal drug. It is a monohydroxyquinoline and an organochlorine compound. It is functionally related to a quinolin-8-ol.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Oc1c(Cl)cc(Cl)c2cccnc12
Identifiers
PDB
CAS-ID773-76-2
RxCUI20875
ChEMBL IDCHEMBL1200596
ChEBI ID59477
PubChem CID2722
DrugBankDB01243
UNII ID
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 95 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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