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Cefoxitin
Mefoxin (cefoxitin) is a small molecule pharmaceutical. Cefoxitin was first approved as Mefoxin on 1982-01-01. It is used to treat abscess, bacterial infections, bacterial skin diseases, bacteroides infections, and clostridium infections amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
digestive system diseasesD004066
respiratory tract diseasesD012140
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cefoxitin sodium
Tradename
Company
Number
Date
Products
CEFOXITIN AND DEXTROSE IN DUPLEX CONTAINERB. Braun MedicalN-065214 RX2006-03-10
2 products, RLD, RS
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Labels
FDA
EMA
Brand Name
Status
Last Update
cefoxitinANDA2023-04-17
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
abscessEFO_0003030D000038—
bacterial infections—D001424A49
bacterial skin diseases—D017192—
bacteroides infectionsEFO_1000832D001442—
clostridium infectionsEFO_1000874D003015A05.2
escherichia coli infectionsEFO_1001318D004927B96.20
gonorrheaDOID_7551D006069A54
haemophilus infectionsEFO_1001127D006192—
infectious bone diseases—D001850—
infectious pregnancy complications—D011251—
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DC: Second-generation cephalosporins
— J01DC01: Cefoxitin
HCPCS
Code
Description
J0694
Injection, cefoxitin sodium, 1 gm
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver cirrhosisD008103EFO_0001422K74.0————22
Esophageal and gastric varicesD004932EFO_0009545I85————22
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCEFOXITIN
INNcefoxitin
Description
Cefoxitin is a semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase. It has a role as an antibacterial drug. It is a cephalosporin, a semisynthetic derivative, a beta-lactam antibiotic allergen and a cephamycin. It is a conjugate acid of a cefoxitin(1-).
Classification
Small molecule
Drug classcephalosporins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CO[C@@]1(NC(=O)Cc2cccs2)C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@@H]21
Identifiers
PDB—
CAS-ID35607-66-0
RxCUI2189
ChEMBL IDCHEMBL996
ChEBI ID209807
PubChem CID441199
DrugBankDB01331
UNII ID6OEV9DX57Y (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 16,198 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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162 adverse events reported
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