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Cefazolin
Ancef, Kefzol (cefazolin) is a small molecule pharmaceutical. Cefazolin was first approved as Ancef on 1982-01-01. It is used to treat bacterial endocarditis, bacterial infections, bacterial pneumonia, bacterial skin diseases, and escherichia coli infections amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
wounds and injuriesD014947
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cefazolin sodium
Tradename
Company
Number
Date
Products
CEFAZOLIN AND DEXTROSEB. Braun MedicalN-050779 RX2000-07-27
2 products, RLD, RS
CEFAZOLIN IN PLASTIC CONTAINERBaxterN-207131 RX2015-08-07
2 products, RLD, RS
CEFAZOLIN SODIUMHikma PharmaceuticalsN-216109 RX2022-10-07
2 products, RLD, RS
CEFAZOLIN SODIUMHQ Specialty PharmaN-211413 RX2023-05-08
1 products, RLD, RS
Show 4 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
cefazolinANDA2023-06-06
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial endocarditisEFO_1000830D004697—
bacterial infections—D001424A49
bacterial pneumoniaEFO_1001272D018410J15.9
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
human bites—D001734W50.3
klebsiella infectionsEFO_1001353D007710—
proteus infectionsEFO_1001130D011512—
soft tissue infections—D018461—
staphylococcal infections—D013203A49.01
Show 2 more
Agency Specific
FDA
EMA
Expiration
Code
CEFAZOLIN SODIUM, CEFAZOLIN AND DEXTROSE, B BRAUN
2023-11-23NPP
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DB: First-generation cephalosporins
— J01DB04: Cefazolin
HCPCS
Code
Description
J0690
Injection, cefazolin sodium, 500 mg
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial infectionsD001424A49———1—1
Breast implantationD019928———1—1
Urinary tract infectionsD014552EFO_0003103N39.0———1—1
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pulmonary tuberculosisD014397EFO_1000049A15—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—4————4
OsteomyelitisD010019EFO_0003102M861————1
Infectious arthritisD001170EFO_1001351M001————1
PyomyositisD052880EFO_1001409M60.01————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MastitisD008413EFO_1001034N61————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCEFAZOLIN
INNcefazolin
Description
Cefazolin is a first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively. It has a role as an antibacterial drug. It is a cephalosporin, a member of thiadiazoles, a member of tetrazoles and a beta-lactam antibiotic allergen. It is a conjugate acid of a cefazolin(1-).
Classification
Small molecule
Drug classcephalosporins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1nnc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)Cn4cnnn4)[C@H]3SC2)s1
Identifiers
PDB—
CAS-ID25953-19-9
RxCUI2180
ChEMBL IDCHEMBL1435
ChEBI ID474053
PubChem CID33255
DrugBankDB01327
UNII IDIHS69L0Y4T (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 20,063 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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498 adverse events reported
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