Skip to content
Betamethasone
Beta-val, Celestone, Diprolene, Enstilar, Lotrisone, Luxiq, Sernivo, Taclonex, Uticort, Wynzora (betamethasone) is a small molecule pharmaceutical. Betamethasone was first approved as Celestone on 1982-01-01. It is used to treat atopic dermatitis, facial dermatoses, foot dermatoses, hand dermatoses, and inflammation amongst others in the USA. The pharmaceutical is active against glucocorticoid receptor.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
hereditary congenital and neonatal diseases and abnormalitiesD009358
skin and connective tissue diseasesD017437
immune system diseasesD007154
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Beta-val, Diprolene, Luxiq, Sernivo (generic drugs available since 1984-10-10, discontinued: Alphatrex, Betaderm, Betatrex, Celestone, Diprosone, Uticort, Valisone)
Combinations
Celestone soluspan, Enstilar, Taclonex, Wynzora (generic drugs available since 1984-10-10, discontinued: Lotrisone)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Betamethasone
Tradename
Company
Number
Date
Products
CELESTONEMerck Sharp & DohmeN-014215 DISCN1982-01-01
1 products
CELESTONEMerck Sharp & DohmeN-012657 DISCN1982-01-01
1 products
CELESTONEMerck Sharp & DohmeN-014762 DISCN1982-01-01
1 products
Hide discontinued
Betamethasone acetate
+
Betamethasone sodium phosphate
Tradename
Company
Number
Date
Products
CELESTONE SOLUSPANOrganonN-014602 RX1982-01-01
1 products, RLD, RS
Betamethasone benzoate
Tradename
Company
Number
Date
Products
UTICORTPfizerN-016998 DISCN1982-01-01
1 products
UTICORTPfizerN-017244 DISCN1982-01-01
1 products
UTICORTPfizerN-017528 DISCN1982-01-01
1 products
UTICORTPfizerN-018089 DISCN1982-01-01
1 products
Hide discontinued
Betamethasone dipropionate
Tradename
Company
Number
Date
Products
BETAMETHASONE DIPROPIONATEFougera PharmaceuticalsN-019137 RX1984-06-26
1 products, RLD, RS
BETAMETHASONE DIPROPIONATEFougera PharmaceuticalsN-019141 RX1984-09-04
1 products, RLD, RS
DIPROLENEOrganonN-018741 RX1983-07-27
1 products, RLD, RS
SERNIVOPrimus PharmaceuticalsN-208079 RX2016-02-05
1 products, RLD, RS
Show 11 discontinued
Betamethasone dipropionate
+
Calcipotriene
Tradename
Company
Number
Date
Products
TACLONEXLEO PharmaN-021852 RX2006-01-09
1 products, RLD, RS
TACLONEXLEO PharmaN-022185 RX2008-05-09
1 products, RLD, RS
ENSTILARLEO PharmaN-207589 RX2015-10-16
1 products, RLD, RS
WYNZORAMC2 TherapeuticsN-213422 RX2020-07-20
1 products, RLD, RS
Betamethasone dipropionate
+
Clotrimazole
Tradename
Company
Number
Date
Products
LOTRISONEMerck Sharp & DohmeN-020010 DISCN2000-12-08
1 products, RLD
LOTRISONEOrganonN-018827 DISCN1984-07-10
1 products, RLD
Hide discontinued
Betamethasone sodium phosphate
Tradename
Company
Number
Date
Products
CELESTONEMerck Sharp & DohmeN-017561 DISCN1982-01-01
1 products, RLD
Hide discontinued
Betamethasone valerate
Tradename
Company
Number
Date
Products
BETA-VALCosette Pharmaceuticals N-018642 RX1983-03-24
1 products
BETAMETHASONE VALERATEFougera PharmaceuticalsN-018861 RX1983-08-31
1 products, RLD, RS
BETAMETHASONE VALERATEFougera PharmaceuticalsN-018865 RX1983-08-31
1 products, RLD, RS
BETAMETHASONE VALERATEFougera PharmaceuticalsN-018866 RX1983-08-31
1 products, RLD, RS
LUXIQMylanN-020934 RX1999-02-28
1 products, RLD, RS
Show 10 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
betamethasone dipropionateANDA2023-02-14
celestone soluspanNew Drug Application2021-06-01
diproleneNew Drug Application2021-06-01
enstilarNew Drug Application2021-10-18
luxiqNew Drug Application2018-04-30
sernivoNew Drug Application2021-06-23
taclonexNew Drug Application2022-05-24
wynzoraNew Drug Application2021-12-22
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
atopic dermatitisEFO_0000274D003876L20
facial dermatosesD005148
foot dermatosesD005533
hand dermatosesD006229
inflammationMP_0001845D007249
leg dermatosesD007868
pruritus aniD011538L29.0
psoriasisEFO_0000676D011565L40
scalp dermatosesD012536
seborrheic dermatitisD012628L21
Agency Specific
FDA
EMA
Expiration
Code
BETAMETHASONE DIPROPIONATE / CALCIPOTRIENE, WYNZORA, MC2
2023-07-20NDF
BETAMETHASONE DIPROPIONATE / CALCIPOTRIENE, ENSTILAR, LEO PHARMA AS
2023-01-30PED
BETAMETHASONE DIPROPIONATE / CALCIPOTRIENE, TACLONEX, LEO PHARMA AS
2023-01-25PED
Patent Expiration
Patent
Expires
Flag
FDA Information
Betamethasone Dipropionate / Calcipotriene, Enstilar, Leo Pharma As
91197812031-06-10DPU-1761, U-2627
95662862031-06-10DP
101306402031-06-10DP
106176982031-06-10DP
106609082031-06-10DPU-2627
106823642031-06-10DP
106881082031-06-10U-2627
107167992031-06-10DP
Betamethasone Dipropionate, Sernivo, Primus Pharms
93644852030-08-31DPU-1858
94336302030-08-31DPU-1858
94399112030-08-31DPU-1858
96559072030-08-31DPU-1858
97758512030-08-31DPU-1858
98779742030-08-31DPU-1858
101791372030-08-31DPU-1858
Betamethasone Dipropionate / Calcipotriene, Wynzora, Mc2
102652652027-09-27DP
ATC Codes
A: Alimentary tract and metabolism drugs
A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
A07E: Intestinal antiinflammatory agents
A07EA: Corticosteroids acting locally
A07EA04: Betamethasone
C: Cardiovascular system drugs
C05: Vasoprotectives
C05A: Agents for treatment of hemorrhoids and anal fissures for topical use
C05AA: Corticosteroids, topical for treatment of hemorrhoids and anal fissures
C05AA05: Betamethasone
D: Dermatologicals
D07: Corticosteroids, dermatological preparations
D07A: Corticosteroid dermatological preparations, plain
D07AC: Corticosteroids, potent (group iii)
D07AC01: Betamethasone
D07B: Corticosteroids, combinations with antiseptics
D07BC: Corticosteroids, potent, combinations with antiseptics
D07BC01: Betamethasone and antiseptics
D07C: Corticosteroids, combinations with antibiotics
D07CC: Corticosteroids, potent, combinations with antibiotics
D07CC01: Betamethasone and antibiotics
D07X: Corticosteroids, other combinations
D07XC: Corticosteroids, potent, other combinations
D07XC01: Betamethasone
H: Systemic hormonal preparations, excl. sex hormones and insulins
H02: Corticosteroids for systemic use
H02A: Corticosteroids for systemic use, plain
H02AB: Glucocorticoids, systemic
H02AB01: Betamethasone
R: Respiratory system drugs
R01: Nasal preparations
R01A: Decongestants and other nasal preparations for topical use
R01AD: Corticosteroid nasal preparations for topical use
R01AD06: Betamethasone
R03: Drugs for obstructive airway diseases
R03B: Other drugs for obstructive airway diseases, inhalants in atc
R03BA: Glucocorticoid inhalants for obstructive airway disease
R03BA04: Betamethasone
S: Sensory organ drugs
S01: Ophthalmologicals
S01B: Antiinflammatory agents, ophthalmologic
S01BA: Corticosteroid ophthalmologic antiinflammatory agents, plain
S01BA06: Betamethasone
S01BB: Corticosteroids and mydriatics in combination
S01BB04: Betamethasone and mydriatics
S01C: Antiinflammatory agents and antiinfectives in combination
S01CA: Corticosteroids and antiinfectives in combination, opthalmologic
S01CA05: Betamethasone and antiinfectives
S01CB: Corticosteroids/antiinfectives/mydriatics in combination
S01CB04: Betamethasone
S02: Otologicals
S02B: Corticosteroid otologicals
S02BA: Corticosteroids
S02BA07: Betamethasone
S03: Ophthalmological and otological preparations
S03B: Corticosteroid ophthalmologic and otologic preparations
S03BA: Corticosteroids
S03BA03: Betamethasone
S03C: Corticosteroids and antiinfectives in combination, opthalmologic and otologic
S03CA: Corticosteroids and antiinfectives in combination
S03CA06: Betamethasone and antiinfectives
HCPCS
Code
Description
J0702
Injection, betamethasone acetate 3 mg and betamethasone sodium phosphate 3 mg
J7624
Betamethasone, inhalation solution, compounded product, administered through dme, unit dose form, per milligram
Clinical
Clinical Trials
28 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Depressive disorderD003866EFO_1002014F32.A11
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
XerostomiaD014987K11.7112
Hepatitis cD006526B19.2111
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-alcoholic fatty liver diseaseD065626EFO_0003095K75.81112
ObesityD009765EFO_0001073E66.911
HyperoxaluriaD006959E72.5311
OverweightD050177E66.3111
HomocystinuriaD006712E72.1111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients268
Chronic hepatitis cD019698EFO_0004220B18.2112
RecurrenceD01200811
Male infertilityD007248EFO_0004248N4611
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiovascular diseasesD002318EFO_0000319I9822
Nervous system diseasesD009422G00-G9911
Angelman syndromeD017204Orphanet_72Q93.5111
Insulin resistanceD007333EFO_000261411
MucositisD052016EFO_100189811
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameBETAMETHASONE
INNbetamethasone
Description
Betamethasone is a glucocorticoid, a 20-oxo steroid, a 21-hydroxy steroid, a 17alpha-hydroxy steroid, a fluorinated steroid, an 11beta-hydroxy steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, an anti-asthmatic agent and an immunosuppressive agent. It derives from a hydride of a pregnane.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
Identifiers
PDB
CAS-ID378-44-9
RxCUI1514
ChEMBL IDCHEMBL632
ChEBI ID3077
PubChem CID9782
DrugBankDB00443
UNII ID9842X06Q6M (ChemIDplus, GSRS)
Target
Agency Approved
NR3C1
NR3C1
Organism
Homo sapiens
Gene name
NR3C1
Gene synonyms
GRL
NCBI Gene ID
Protein name
glucocorticoid receptor
Protein synonyms
Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3 group C member 1 variant hGR-B(54), nuclear receptor subfamily 3 group C member 1 variant hGR-B(77), nuclear receptor subfamily 3 group C member 1 variant hGR-B(93), nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Uniprot ID
Mouse ortholog
Nr3c1 (14815)
glucocorticoid receptor (Q61629)
Alternate
No data
Variants
Clinical Variant
No data
Financial
Wynzora - Novan
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Diprosone - Organon
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 12,770 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
671 adverse events reported
View more details