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Benzquinamide
Emete-con (benzquinamide) is a small molecule pharmaceutical. Benzquinamide was first approved as Emete-con on 1982-01-01. It is used to treat nausea and vomiting in the USA. The pharmaceutical is active against prostaglandin G/H synthase 2 and D(2) dopamine receptor.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Benzquinamide hydrochloride
Tradename
Company
Number
Date
Products
EMETE-CONMylanN-016820 DISCN1982-01-01
1 products
EMETE-CONRoerigN-016818 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
nauseaHP_0002018D009325R11.0
vomitingHP_0002013D014839R11.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
178 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Acne vulgarisD000152EFO_0003894L709423421896
PainD010146EFO_0003843R5221115
PharyngitisD010612R07.0213
Postoperative painD010149G89.18112
Type 2 diabetes mellitusD003924EFO_0001360E1111
ToothacheD014098K08.8911
Healthy volunteers/patients11
Dental pinsD00377211
Skin diseasesD012871L00-L9911
Propionibacterium acnesD011425NCBITaxon_174711
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ischemic strokeD00008324211
HyperglycemiaD006943HP_0003074R73.911
EczemaD004485HP_0000964L30.911
InfectionsD007239EFO_000054411
Chronic renal insufficiencyD051436N1811
Gastroesophageal refluxD005764EFO_0003948K2111
DyspepsiaD004415EFO_0008533K3011
Abdominal painD015746R10.911
Malabsorption syndromesD008286EFO_0009554K9011
Stomach diseasesD013272111
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Local anesthesiaD000772123
Surgical wound infectionD013530112
Actinic keratosisD055623L57.011
Critical illnessD01663811
Cerebrovascular disordersD002561EFO_0003763I60-I6911
Dental anesthesiaD000766111
AsthmaD001249EFO_0000270J4511
Otitis mediaD010033EFO_0004992H66.911
GingivitisD005891K05.10111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Oral lichen planusD017676123
ObesityD009765EFO_0001073E66.9112
Oral ulcerD019226HP_000015511
Staphylococcal infectionsD013203A49.0111
RosaceaD012393L7111
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypotensionD007022EFO_0005251I9511
Orthodontic anchorage proceduresD05228011
Body weightD001835EFO_000433811
Glucose metabolism disordersD04488211
Lichen planusD008010L4311
Liver diseasesD008107EFO_0001421K70-K7711
Weight lossD015431HP_000182411
Feeding behaviorD00524711
Duchenne muscular dystrophyD02038811
ScoliosisD012600EFO_0004273M4111
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBENZQUINAMIDE
INNbenzquinamide
Description
Benzquinamide is a monocarboxylic acid amide. It has a role as an antiemetic, a sedative, a H1-receptor antagonist, a muscarinic antagonist and an antipsychotic agent.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(C)=O
Identifiers
PDB
CAS-ID63-12-7
RxCUI19041
ChEMBL IDCHEMBL1201250
ChEBI ID27662
PubChem CID2342
DrugBankDB00767
UNII ID0475EA27Q3 (ChemIDplus, GSRS)
Target
Agency Approved
PTGS2
PTGS2
DRD2
DRD2
Organism
Homo sapiens
Gene name
PTGS2
Gene synonyms
COX2
NCBI Gene ID
Protein name
prostaglandin G/H synthase 2
Protein synonyms
COX-2, cyclooxygenase 2, cyclooxygenase 2b, Cyclooxygenase-2, PGH synthase 2, PGHS-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Uniprot ID
Mouse ortholog
Ptgs2 (19225)
prostaglandin G/H synthase 2 (Q543K3)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 34 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,814 adverse events reported
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