Skip to content
Acebutolol
Sectral (acebutolol) is a small molecule pharmaceutical. Acebutolol was first approved as Sectral on 1984-12-28. It is used to treat angina pectoris, hypertension, myocardial infarction, ventricular fibrillation, and ventricular tachycardia in the USA. The pharmaceutical is active against beta-1 adrenergic receptor.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acebutolol hydrochloride
Tradename
Company
Number
Date
Products
SECTRALPromius PharmaN-018917 DISCN1984-12-28
2 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
acebutolol hydrochlorideANDA2023-04-26
sectralNew Drug Application2012-01-12
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
angina pectorisEFO_0003913D000787I20
hypertensionEFO_0000537D006973I10
myocardial infarctionEFO_0000612D009203I21
ventricular fibrillationEFO_0004287D014693I49.01
ventricular tachycardiaD017180I47.2
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
C07: Beta-adrenergic blocking agents
C07A: Beta blocking agents
C07AB: Beta blocking agents, selective
C07AB04: Acebutolol
C07B: Beta blocking agents and thiazides
C07BB: Beta blocking agents, selective, and thiazides
C07BB04: Acebutolol and thiazides
HCPCS
No data
Clinical
Clinical Trials
38 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AlcoholismD000437EFO_0003829F10.117312325
SchizophreniaD012559EFO_0000692F20213
Anxiety disordersD001008EFO_0006788F41.1112
Major depressive disorderD003865EFO_0003761F22112
Bipolar disorderD001714EFO_0000289F30.91112
Psychotic disordersD011618F20.8111
GamblingD005715F63.011
Social phobiaD000072861EFO_1001917F40.111
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DementiaD003704F0311
Psychophysiologic disordersD011602F45.911
DepressionD003863F33.911
Binge-eating disorderD056912F50.2111
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Fragile x syndromeD005600Q99.2213
Alcohol-related disordersD019973F1011
Healthy volunteers/patients11
Autism spectrum disorderD000067877F84.011
Cocaine-related disordersD019970F1411
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
TinnitusD014012HP_0000360H93.111
Autistic disorderD001321EFO_0003758F84.011
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Parkinson diseaseD010300EFO_0002508G2011
AnxietyD001007EFO_0005230F41.111
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameACEBUTOLOL
INNacebutolol
Description
Acebutolol is an ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol. It has a role as a beta-adrenergic antagonist, an anti-arrhythmia drug, an antihypertensive agent and a sympathomimetic agent. It is a member of ethanolamines, a propanolamine, a secondary amino compound, an ether, a monocarboxylic acid amide and an aromatic amide. It is a conjugate base of an acebutolol(1+).
Classification
Small molecule
Drug classbeta-blockers (propranolol type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C(C)=O)c1
Identifiers
PDB
CAS-ID37517-30-9
RxCUI149
ChEMBL IDCHEMBL642
ChEBI ID2379
PubChem CID1978
DrugBankDB01193
UNII ID67P356D8GH (ChemIDplus, GSRS)
Target
Agency Approved
ADRB1
ADRB1
Organism
Homo sapiens
Gene name
ADRB1
Gene synonyms
ADRB1R, B1AR
NCBI Gene ID
Protein name
beta-1 adrenergic receptor
Protein synonyms
adrenergic, beta-1-, receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor
Uniprot ID
Mouse ortholog
Adrb1 (11554)
beta-1 adrenergic receptor (P34971)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,289 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
867 adverse events reported
View more details